Courtesy of Tris Pharma Medical Affairs.

This site is intended for U.S. healthcare professionals only.

Study designs Crossover75 Crossover75

Patients are randomized to a sequence of treatments, and they cross over from one treatment to another during the course of the trial

Each treatment occurs in a time period with a washout period in between
Each patient serves as their own control, which reduces the potential for mean variability; however, there are potential problems with carryover effects (i.e., residual effects)


75. Pennsylvania State University. STAT 509: Design and Analysis of Clinical Trials. 3.3: Experimental Design Terminology. Available at